Gene networking in colistin-induced nephrotoxicity reveals an adverse outcome pathway triggered by proteotoxic stress

Colistin has been widely used for the treatment of infections of multidrug-resistant Gram-negative bacteria, despite the fact that it induces serious kidney injury as a side effect. To investigate the mechanism underlying its nephrotoxicity, colistin methanesulfonate sodium (CMS; 25 or 50 mg/kg) was...

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Detalles Bibliográficos
Autores principales: Lee, Eun Hee, Kim, Soojin, Choi, Mi-Sun, Yang, Heeyoung, Park, Se-Myo, Oh, Hyun-A, Moon, Kyoung-Sik, Han, Ji-Seok, Kim, Yong-Bum, Yoon, Seokjoo, Oh, Jung-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365082/
https://www.ncbi.nlm.nih.gov/pubmed/30628653
http://dx.doi.org/10.3892/ijmm.2019.4052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365082/
https://www.ncbi.nlm.nih.gov/pubmed/30628653
http://dx.doi.org/10.3892/ijmm.2019.4052

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