DNMT3A/3B overexpression might be correlated with poor patient survival, hypermethylation and low expression of ESR1/PGR in endometrioid carcinoma: an analysis of The Cancer Genome Atlas

BACKGROUND: DNA methylation is involved in numerous biologic events and associates with transcriptional gene silencing, playing an important role in the pathogenesis of endometrial cancer. ESR1/PGR frequently undergoes de novo methylation and loss expression in a wide variety of tumors, including br...

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Detalles Bibliográficos
Autores principales: He, Dan, Wang, Xiao, Zhang, Yan, Zhao, Jian, Han, Rui, Dong, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365298/
https://www.ncbi.nlm.nih.gov/pubmed/30614867
http://dx.doi.org/10.1097/CM9.0000000000000054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365298/
https://www.ncbi.nlm.nih.gov/pubmed/30614867
http://dx.doi.org/10.1097/CM9.0000000000000054

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