Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability

Multiple myeloma (MM) is a largely incurable haematological malignancy defined by the clonal proliferation of malignant plasma cells (PCs) within the bone marrow. Clonal heterogeneity has recently been established as a feature in MM, however, the subclonal evolution associated with disease progressi...

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Detalles Bibliográficos
Autores principales: Dutta, Ankit K., Fink, J. Lynn, Grady, John P., Morgan, Gareth J., Mullighan, Charles G., To, Luen B., Hewett, Duncan R., Zannettino, Andrew C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365384/
https://www.ncbi.nlm.nih.gov/pubmed/30046162
http://dx.doi.org/10.1038/s41375-018-0206-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365384/
https://www.ncbi.nlm.nih.gov/pubmed/30046162
http://dx.doi.org/10.1038/s41375-018-0206-x

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