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Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability
Multiple myeloma (MM) is a largely incurable haematological malignancy defined by the clonal proliferation of malignant plasma cells (PCs) within the bone marrow. Clonal heterogeneity has recently been established as a feature in MM, however, the subclonal evolution associated with disease progressi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365384/ https://www.ncbi.nlm.nih.gov/pubmed/30046162 http://dx.doi.org/10.1038/s41375-018-0206-x |