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Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis

Hemophagocytic lymphohistocytosis (HLH) is characterized by fulminant cytokine storm leading to multiple organ dysfunction and high mortality. HLH is classified into familial (fHLH) and into secondary (sHLH). fHLH is rare and it is due to mutations of genes encoding for perforin or excretory granule...

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Detalles Bibliográficos
Autores principales: Karakike, Eleni, Giamarellos-Bourboulis, Evangelos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365431/
https://www.ncbi.nlm.nih.gov/pubmed/30766533
http://dx.doi.org/10.3389/fimmu.2019.00055