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Suppressor of Cytokine Signaling 3 (SOCS3) Degrades p65 and Regulate HIV-1 Replication

Human Immunodeficiency Virus-1 (HIV-1) is known to induce the expression of SOCS3 which is a negative feed-back regulator of inflammatory responses. Here, we demonstrate that reactivation of latent HIV-1 leads to degradation of SOCS3 at early time points. Interestingly, SOCS3 degradation following t...

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Detalles Bibliográficos
Autores principales: Sood, Vikas, Lata, Sneh, Ramachandran, Vishnampettai G., Banerjea, Akhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365456/
https://www.ncbi.nlm.nih.gov/pubmed/30766526
http://dx.doi.org/10.3389/fmicb.2019.00114