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AntagomiR-103 and -107 Treatment Affects Cardiac Function and Metabolism

MicroRNA-103/107 regulate systemic glucose metabolism and insulin sensitivity. For this reason, inhibitory strategies for these microRNAs are currently being tested in clinical trials. Given the high metabolic demands of the heart and the abundant cardiac expression of miR-103/107, we questioned whe...

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Detalles Bibliográficos
Autores principales: Rech, Monika, Kuhn, Annika R., Lumens, Joost, Carai, Paolo, van Leeuwen, Rick, Verhesen, Wouter, Verjans, Robin, Lecomte, Julie, Liu, Yilin, Luiken, Joost J.F.P., Mohren, Ronny, Cillero-Pastor, Berta, Heymans, Stephane, Knoops, Kèvin, van Bilsen, Marc, Schroen, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365487/
https://www.ncbi.nlm.nih.gov/pubmed/30731323
http://dx.doi.org/10.1016/j.omtn.2018.12.010