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miR-148a regulates expression of the transferrin receptor 1 in hepatocellular carcinoma

Transferrin receptor 1 (TFR1) is a transmembrane glycoprotein that allows for transferrin-bound iron uptake in mammalian cells. It is overexpressed in various cancers to satisfy the high iron demand of fast proliferating cells. Here we show that in hepatocellular carcinoma (HCC) TFR1 expression is r...

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Detalles Bibliográficos
Autores principales: Babu, Kamesh R., Muckenthaler, Martina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365501/
https://www.ncbi.nlm.nih.gov/pubmed/30728365
http://dx.doi.org/10.1038/s41598-018-35947-7