Pasireotide protects mammalian cochlear hair cells from gentamicin ototoxicity by activating the PI3K–Akt pathway

Gentamicin is a widely used antibiotic for the treatment of gram-negative bacterial infections; however, its use often results in significant and permanent hearing loss. Hearing loss resulting from hair cell (HC) degeneration affects millions of people worldwide, and one major cause is the loss of s...

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Detalles Bibliográficos
Autores principales: Kucharava, Krystsina, Sekulic-Jablanovic, Marijana, Horvath, Lukas, Bodmer, Daniel, Petkovic, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365508/
https://www.ncbi.nlm.nih.gov/pubmed/30728348
http://dx.doi.org/10.1038/s41419-019-1386-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365508/
https://www.ncbi.nlm.nih.gov/pubmed/30728348
http://dx.doi.org/10.1038/s41419-019-1386-7

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