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Pasireotide protects mammalian cochlear hair cells from gentamicin ototoxicity by activating the PI3K–Akt pathway
Gentamicin is a widely used antibiotic for the treatment of gram-negative bacterial infections; however, its use often results in significant and permanent hearing loss. Hearing loss resulting from hair cell (HC) degeneration affects millions of people worldwide, and one major cause is the loss of s...
Autores principales: | Kucharava, Krystsina, Sekulic-Jablanovic, Marijana, Horvath, Lukas, Bodmer, Daniel, Petkovic, Vesna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365508/ https://www.ncbi.nlm.nih.gov/pubmed/30728348 http://dx.doi.org/10.1038/s41419-019-1386-7 |
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