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The RGD motif is involved in CD97/ADGRE5-promoted cell adhesion and viability of HT1080 cells

CD97/ADGRE5 is an adhesion G protein-coupled receptor (aGPCR) involved in tumor cell adhesion, migration, angiogenesis, and apoptosis. CD97 has been shown previously to stimulate angiogenesis by interacting with integrins on endothelial cells via an Arginine-Glycine-Aspartic acid (RGD) motif. In thi...

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Detalles Bibliográficos
Autores principales: Tjong, Wen-Ye, Lin, Hsi-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365523/
https://www.ncbi.nlm.nih.gov/pubmed/30728423
http://dx.doi.org/10.1038/s41598-018-38045-w