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Effect of Chemical Permeation Enhancers on Skin Permeability: In silico screening using Molecular Dynamics simulations
Breaching of the skin barrier is essential for delivering active pharmaceutical ingredients (APIs) for pharmaceutical, dermatological and aesthetic applications. Chemical permeation enhancers (CPEs) are molecules that interact with the constituents of skin’s outermost and rate limiting layer stratum...
Autores principales: | Gupta, Rakesh, Dwadasi, Balarama Sridhar, Rai, Beena, Mitragotri, Samir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365548/ https://www.ncbi.nlm.nih.gov/pubmed/30728438 http://dx.doi.org/10.1038/s41598-018-37900-0 |
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