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Cytoplasmic Asporin promotes cell migration by regulating TGF-β/Smad2/3 pathway and indicates a poor prognosis in colorectal cancer

Previous studies revealed that Asporin (ASPN) is a potential mediator in the development of various types of cancer as a secreted stroma protein, but the function of ASPN inside the cancer cells remains largely unknown. Here, we demonstrated a higher expression level of ASPN in colorectal cancer (CR...

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Detalles Bibliográficos
Autores principales: Li, Hengcun, Zhang, Zheng, Chen, Lei, Sun, Xiujing, Zhao, Yu, Guo, Qingdong, Zhu, Shengtao, Li, Peng, Min, Li, Zhang, Shutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365561/
https://www.ncbi.nlm.nih.gov/pubmed/30728352
http://dx.doi.org/10.1038/s41419-019-1376-9