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Crystal structure of the dog allergen Can f 6 and structure-based implications of its cross-reactivity with the cat allergen Fel d 4

Several dog allergens cause allergic reactions in humans worldwide. Seven distinct dog allergens, designated Canis familiaris allergen 1 to 7 (Can f 1–Can f 7), have been identified thus far. Can f 6 shows high sequence similarity and cross-reactivity with Fel d 4 and Equ c 1, major cat and horse al...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kenji, Ishibashi, Osamu, Sugiura, Keisuke, Ubatani, Miki, Sakaguchi, Masaya, Nakatsuji, Masatoshi, Shimamoto, Shigeru, Noda, Masanori, Uchiyama, Susumu, Fukutomi, Yuma, Nishimura, Shigenori, Inui, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365566/
https://www.ncbi.nlm.nih.gov/pubmed/30728436
http://dx.doi.org/10.1038/s41598-018-38134-w