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Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis

Nicotinamide phosphoribosyltransferase (NAMPT) functions in NAD synthesis, apoptosis, and inflammation. Dysregulation of NAMPT has been associated with several inflammatory diseases, including rheumatoid arthritis (RA). The purpose of this study was to investigate NAMPT’s role in arthritis using mou...

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Detalles Bibliográficos
Autores principales: Li, Xuanan, Islam, Shamima, Xiong, Min, Nsumu, Ndona N., Lee, Mark W., Zhang, Li Qin, Ueki, Yasuyoshi, Heruth, Daniel P., Lei, Guanghua, Ye, Shui Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365567/
https://www.ncbi.nlm.nih.gov/pubmed/30774990
http://dx.doi.org/10.1038/s41420-018-0134-6