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Aryl Azides as Phosphine-Activated Switches for Small Molecule Function
Engineered small molecule triggers are important tools for the control and investigation of biological processes, in particular protein function. Staudinger reductions of aryl azides to amines through the use of phosphines can trigger an elimination reaction, and thereby activation of a functional m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365568/ https://www.ncbi.nlm.nih.gov/pubmed/30728367 http://dx.doi.org/10.1038/s41598-018-37023-6 |