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Differential expression of CXCR3 and CCR6 on CD4(+) T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome

Immune reconstitution inflammatory syndrome (IRIS) occurs in up to 40% of individuals co-infected with pulmonary tuberculosis (PTB) and HIV, primarily upon antiretroviral therapy (ART) initiation. Phenotypic changes in T-cells during TB-IRIS and their relationship with systemic inflammation are not...

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Detalles Bibliográficos
Autores principales: Silveira-Mattos, Paulo S., Narendran, Gopalan, Akrami, Kevan, Fukutani, Kiyoshi F., Anbalagan, Selvaraj, Nayak, Kaustuv, Subramanyam, Sudha, Subramani, Rajasekaran, Vinhaes, Caian L., Souza, Deivide Oliveira-de, Antonelli, Lis R., Satagopan, Kumar, Porter, Brian O., Sher, Alan, Swaminathan, Soumya, Sereti, Irini, Andrade, Bruno B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365576/
https://www.ncbi.nlm.nih.gov/pubmed/30728405
http://dx.doi.org/10.1038/s41598-018-37846-3