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Genome-wide profiling of human papillomavirus DNA integration in liquid-based cytology specimens from a Gabonese female population using HPV capture technology

Human papillomavirus (HPV) is recognised as the cause of precancerous and cancerous cervical lesions. Furthermore, in high-grade lesions, HPV is frequently integrated in the host cell genome and associated with the partial or complete loss of the E1 and E2 genes, which regulate the activity of viral...

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Detalles Bibliográficos
Autores principales: Nkili-Meyong, Andriniaina Andy, Moussavou-Boundzanga, Pamela, Labouba, Ingrid, Koumakpayi, Ismaël Hervé, Jeannot, Emmanuelle, Descorps-Declère, Stéphane, Sastre-Garau, Xavier, Leroy, Eric M., Belembaogo, Ernest, Berthet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365579/
https://www.ncbi.nlm.nih.gov/pubmed/30728408
http://dx.doi.org/10.1038/s41598-018-37871-2