p53 induces senescence through Lamin A/C stabilization-mediated nuclear deformation

p53-mediated cellular senescence has been intensively investigated, because it is important for tumor suppressive function. In addition, p16/INK4A is well known to be critical for cellular senescence. However, detailed molecular mechanism or relevance between p53 and p16-mediated senescence has not...

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Detalles Bibliográficos
Autores principales: Yoon, Min-Ho, Kang, So-mi, Lee, Su-Jin, Woo, Tae-Gyun, Oh, Ah-Young, Park, Soyoung, Ha, Nam-Chul, Park, Bum-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365587/
https://www.ncbi.nlm.nih.gov/pubmed/30728349
http://dx.doi.org/10.1038/s41419-019-1378-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365587/
https://www.ncbi.nlm.nih.gov/pubmed/30728349
http://dx.doi.org/10.1038/s41419-019-1378-7

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