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The Vacuolar Ca(2+) ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis

Calcium is a critically important secondary messenger of intracellular signal transduction in eukaryotes but must be maintained at low levels in the cytoplasm of resting cells to avoid toxicity. This is achieved by several pumps that actively transport excess cytoplasmic Ca(2+) out of the cell acros...

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Detalles Bibliográficos
Autores principales: Luna-Tapia, Arturo, DeJarnette, Christian, Sansevere, Emily, Reitler, Parker, Butts, Arielle, Hevener, Kirk E., Palmer, Glen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365616/
https://www.ncbi.nlm.nih.gov/pubmed/30728284
http://dx.doi.org/10.1128/mSphere.00715-18