Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling

Tetralogy of Fallot (TOF) is the most common cyanotic form of congenital heart defects (CHDs). The right ventricular hypertrophy is associated with the survival rate of patients with repaired TOF. However, very little is known concerning its genetic etiology. Based on mouse model studies, a disinter...

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Detalles Bibliográficos
Autores principales: Xie, Yifang, Ma, Anyun, Wang, Boshi, Peng, Rui, Jing, Yingchun, Wang, Deqian, Finnell, Richard H., Qiao, Bin, Wang, Yongming, Wang, Hongyan, Zheng, Yufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365624/
https://www.ncbi.nlm.nih.gov/pubmed/30610007
http://dx.doi.org/10.1042/CS20180842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365624/
https://www.ncbi.nlm.nih.gov/pubmed/30610007
http://dx.doi.org/10.1042/CS20180842

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