Cargando…

Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling

Tetralogy of Fallot (TOF) is the most common cyanotic form of congenital heart defects (CHDs). The right ventricular hypertrophy is associated with the survival rate of patients with repaired TOF. However, very little is known concerning its genetic etiology. Based on mouse model studies, a disinter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Yifang, Ma, Anyun, Wang, Boshi, Peng, Rui, Jing, Yingchun, Wang, Deqian, Finnell, Richard H., Qiao, Bin, Wang, Yongming, Wang, Hongyan, Zheng, Yufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365624/ https://www.ncbi.nlm.nih.gov/pubmed/30610007 http://dx.doi.org/10.1042/CS20180842

Ejemplares similares

Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain
por: Miller, Miles A., et al.
Publicado: (2015)

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
por: Díaz, Begoña, et al.
Publicado: (2013)

TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2)
por: Chemaly, Melody, et al.
Publicado: (2022)

ADAM23 in Cardiomyocyte Inhibits Cardiac Hypertrophy by Targeting FAK‐AKT Signaling
por: Xiang, Mei, et al.
Publicado: (2018)

Correlation of IL-1 and HB-EGF with endometrial receptivity
por: Wang, Hui, et al.
Publicado: (2018)

ADAM17 is essential for ectodomain shedding of the EGF‐receptor ligand amphiregulin
por: Hosur, Vishnu, et al.
Publicado: (2018)

Identification of the Cancer Cell Proliferation and Survival Functions of proHB-EGF by Using an Anti-HB-EGF Antibody
por: Sato, Shuji, et al.
Publicado: (2013)

MircroRNA-10b Promotes Human Embryonic Stem Cell-Derived Cardiomyocyte Proliferation via Novel Target Gene LATS1
por: Xie, Yifang, et al.
Publicado: (2019)

A Potent Anti-HB-EGF Monoclonal Antibody Inhibits Cancer Cell Proliferation and Multiple Angiogenic Activities of HB-EGF
por: Sato, Shuji, et al.
Publicado: (2012)

Cardiomyocyte cohesion is increased after ADAM17 inhibition
por: Shoykhet, Maria, et al.
Publicado: (2023)

HB-EGF Ameliorates Oxidative Stress-Mediated Uterine Decidualization Damage
por: Yu, Hai-Fan, et al.
Publicado: (2019)

Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers
por: Iwamoto, Ryo, et al.
Publicado: (2016)

APF, HB-EGF, and EGF biomarkers in patients with ulcerative vs. non-ulcerative interstitial cystitis
por: Zhang, Chen-Ou, et al.
Publicado: (2005)

Expression of PRB, FKBP52 and HB-EGF Relating with Ultrasonic Evaluation of Endometrial Receptivity
por: Wang, Ning, et al.
Publicado: (2012)

Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis
por: Wen, Hui-Ju, et al.
Publicado: (2019)

ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling
por: Schmidt, Stefanie, et al.
Publicado: (2018)

Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus
por: Shim, Joon W., et al.
Publicado: (2016)

The GBM Tumor Microenvironment as a Modulator of Therapy Response: ADAM8 Causes Tumor Infiltration of Tams through HB-EGF/EGFR-Mediated CCL2 Expression and Overcomes TMZ Chemosensitization in Glioblastoma
por: Liu, Xiaojin, et al.
Publicado: (2022)

The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release
por: Düsterhöft, Stefan, et al.
Publicado: (2021)

Small GTP‐binding protein Rap1 mediates EGF and HB‐EGF signaling and modulates EGF receptor expression in HTR‐8/SVneo extravillous trophoblast cells
por: Yoshie, Mikihiro, et al.
Publicado: (2023)

Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
por: Yamazaki, Satoru, et al.
Publicado: (2003)

Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion
por: Shimura, Takaya, et al.
Publicado: (2012)

An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation
por: Kim, Yeon Sun, et al.
Publicado: (2023)

H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling
por: Zhang, Yuanzhou, et al.
Publicado: (2019)

HB-EGF Activates the EGFR/HIF-1α Pathway to Induce Proliferation of Arsenic-Transformed Cells and Tumor Growth
por: Wang, Lin, et al.
Publicado: (2020)

Mutagenesis of the ADAM17-phosphatidylserine–binding motif leads to embryonic lethality in mice
por: Veit, Martin, et al.
Publicado: (2019)

PKCα and PKCδ Regulate ADAM17-Mediated Ectodomain Shedding of Heparin Binding-EGF through Separate Pathways
por: Kveiborg, Marie, et al.
Publicado: (2011)

Discovery of HB-EGF binding peptides and their functional characterization in ovarian cancer cell lines
por: Shen, Yanting, et al.
Publicado: (2019)

M2 macrophages reduce the radiosensitivity of head and neck cancer by releasing HB-EGF
por: Fu, Enhui, et al.
Publicado: (2020)

HB-EGF Signaling Is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats
por: Maachi, Hasna, et al.
Publicado: (2020)

Roles for HB‐EGF in Mesenchymal Stromal Cell Proliferation and Differentiation During Skeletal Growth
por: Li, Ping, et al.
Publicado: (2018)

4-[(1-Adamantyl)carbamoyl]pyridinium chloride
por: Wang, Yingchun
Publicado: (2010)

The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein–coupled receptors
por: Yan, Yibing, et al.
Publicado: (2002)

Luteolin suppresses lipopolysaccharide-induced cardiomyocyte hypertrophy and autophagy in vitro
por: Li, Xing, et al.
Publicado: (2019)

NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy
por: Guo, Ningning, et al.
Publicado: (2021)

Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?
por: Földes, Gábor, et al.
Publicado: (2011)

Cardiomyocyte-targeted and 17β-estradiol-loaded acoustic nanoprobes as a theranostic platform for cardiac hypertrophy
por: Zhao, Xueli, et al.
Publicado: (2018)

Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4‐ROS‐ADAM17 pathway
por: Zeng, Si‐yu, et al.
Publicado: (2018)

Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17
por: Moreno-Càceres, J, et al.
Publicado: (2014)

Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway
por: Gunawardhana, Niluka, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_njl9ki8d80uhlvrv6rk1ujbjco