The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1

Ammonia can be utilised as an alternative nitrogen source to glutamine to support cell proliferation. However, the underlying molecular mechanisms and whether all cells have this ability is not fully understood. We find that eleven cancer and non-cancerous cell lines have opposite abilities to toler...

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Detalles Bibliográficos
Autores principales: Lie, Shervi, Wang, Tingting, Forbes, Briony, Proud, Christopher G., Petersen, Janni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365639/
https://www.ncbi.nlm.nih.gov/pubmed/30728400
http://dx.doi.org/10.1038/s41598-018-37509-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365639/
https://www.ncbi.nlm.nih.gov/pubmed/30728400
http://dx.doi.org/10.1038/s41598-018-37509-3

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