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Metabolic Responses to Polymyxin Treatment in Acinetobacter baumannii ATCC 19606: Integrating Transcriptomics and Metabolomics with Genome-Scale Metabolic Modeling

Multidrug-resistant (MDR) Acinetobacter baumannii has emerged as a very problematic pathogen over the past decades, with a high incidence in nosocomial infections. Discovered in the late 1940s but abandoned in the 1970s, polymyxins (i.e., polymyxin B and colistin) have been revived as the last-line...

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Detalles Bibliográficos
Autores principales: Zhu, Yan, Zhao, Jinxin, Maifiah, Mohd Hafidz Mahamad, Velkov, Tony, Schreiber, Falk, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365644/
https://www.ncbi.nlm.nih.gov/pubmed/30746493
http://dx.doi.org/10.1128/mSystems.00157-18