Oxidative Pathways of Deoxyribose and Deoxyribonate Catabolism

Using genome-wide mutant fitness assays in diverse bacteria, we identified novel oxidative pathways for the catabolism of 2-deoxy-d-ribose and 2-deoxy-d-ribonate. We propose that deoxyribose is oxidized to deoxyribonate, oxidized to ketodeoxyribonate, and cleaved to acetyl coenzyme A (acetyl-CoA) an...

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Detalles Bibliográficos
Autores principales: Price, Morgan N., Ray, Jayashree, Iavarone, Anthony T., Carlson, Hans K., Ryan, Elizabeth M., Malmstrom, Rex R., Arkin, Adam P., Deutschbauer, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365646/
https://www.ncbi.nlm.nih.gov/pubmed/30746495
http://dx.doi.org/10.1128/mSystems.00297-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365646/
https://www.ncbi.nlm.nih.gov/pubmed/30746495
http://dx.doi.org/10.1128/mSystems.00297-18

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