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Increasing cellular lifespan with a flow system in organotypic culture of the Laterodorsal Tegmentum (LDT)

Organotypic brain culture is an experimental tool widely used in neuroscience studies. One major drawback of this technique is reduced neuronal survival across time, which is likely exacerbated by the loss of blood flow. We have designed a novel, tube flow system, which is easily incorporated into t...

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Detalles Bibliográficos
Autores principales: Romero-Leguizamón, César R., Elnagar, Mohamed R., Kristiansen, Uffe, Kohlmeier, Kristi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365664/
https://www.ncbi.nlm.nih.gov/pubmed/30728375
http://dx.doi.org/10.1038/s41598-018-37606-3