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Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED

OBJECTIVE: Intestinal autoimmunity with gastrointestinal (GI) dysfunction has been shown in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). Patients lack entero-endocrine (EE) cells and have circulating autoantibodies (Aabs) against critical enzymes in serotoni...

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Detalles Bibliográficos
Autores principales: Naskali, Emmi, Dettmer, Katja, Oefner, Peter J, Pereira, Pedro A B, Krohn, Kai, Auvinen, Petri, Ranki, Annamari, Kluger, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365670/
https://www.ncbi.nlm.nih.gov/pubmed/30608907
http://dx.doi.org/10.1530/EC-18-0513