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Serotonin and tryptophan metabolites, autoantibodies and gut microbiome in APECED
OBJECTIVE: Intestinal autoimmunity with gastrointestinal (GI) dysfunction has been shown in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). Patients lack entero-endocrine (EE) cells and have circulating autoantibodies (Aabs) against critical enzymes in serotoni...
Autores principales: | Naskali, Emmi, Dettmer, Katja, Oefner, Peter J, Pereira, Pedro A B, Krohn, Kai, Auvinen, Petri, Ranki, Annamari, Kluger, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365670/ https://www.ncbi.nlm.nih.gov/pubmed/30608907 http://dx.doi.org/10.1530/EC-18-0513 |
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