Imatinib-induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress

Imatinib is a powerful tyrosine kinase inhibitor that specifically targets BCR-ABL, c-KIT, and PDGFR kinases, and is used in the treatment of chronic myelogenous leukemia, gastrointestinal stromal tumors, and other types of cancers. However, the possible anticancer effects of imatinib in gastric can...

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Detalles Bibliográficos
Autores principales: Kim, Jung Lim, Lee, Dae-Hee, Jeong, Soyeon, Kim, Bo Ram, Na, Yoo Jin, Park, Seong Hye, Jo, Min Jee, Jeong, Yoon A., Oh, Sang Cheul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365688/
https://www.ncbi.nlm.nih.gov/pubmed/30569109
http://dx.doi.org/10.3892/or.2018.6945