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SOCS4 expressed by recombinant HSV protects against cytokine storm in a mouse model

Oncolytic viruses are genetically engineered viruses designed for the treatment of solid tumors, and are often coupled with the antitumor immunity of the host. The challenge of using oncolytic herpes simplex virus (oHSV) as an efficacious oncolytic agent is the potential host tissue damage caused by...

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Detalles Bibliográficos
Autores principales: Ren, Shuqi, Chen, Xiaoqing, Huang, Rongquan, Zhou, Grace Guoying, Yuan, Zhuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365695/
https://www.ncbi.nlm.nih.gov/pubmed/30569160
http://dx.doi.org/10.3892/or.2018.6935