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Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations

Human epidermal growth factor receptor 2 (HER2) is a member of the ErbB family of receptor tyrosine kinases. Numerous studies have reported the amplification and overexpression of HER2 in several types of cancer, including non-small cell lung cancer (NSCLC). However, the benefits of HER2-targeted th...

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Detalles Bibliográficos
Autores principales: Ogoshi, Yusuke, Shien, Kazuhiko, Yoshioka, Takahiro, Torigoe, Hidejiro, Sato, Hiroki, Sakaguchi, Masakiyo, Tomida, Shuta, Namba, Kei, Kurihara, Eisuke, Takahashi, Yuta, Suzawa, Ken, Yamamoto, Hiromasa, Soh, Junichi, Toyooka, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365915/
https://www.ncbi.nlm.nih.gov/pubmed/30854046
http://dx.doi.org/10.3892/ol.2019.9908