Cargando…
Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations
Human epidermal growth factor receptor 2 (HER2) is a member of the ErbB family of receptor tyrosine kinases. Numerous studies have reported the amplification and overexpression of HER2 in several types of cancer, including non-small cell lung cancer (NSCLC). However, the benefits of HER2-targeted th...
Autores principales: | Ogoshi, Yusuke, Shien, Kazuhiko, Yoshioka, Takahiro, Torigoe, Hidejiro, Sato, Hiroki, Sakaguchi, Masakiyo, Tomida, Shuta, Namba, Kei, Kurihara, Eisuke, Takahashi, Yuta, Suzawa, Ken, Yamamoto, Hiromasa, Soh, Junichi, Toyooka, Shinichi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365915/ https://www.ncbi.nlm.nih.gov/pubmed/30854046 http://dx.doi.org/10.3892/ol.2019.9908 |
Ejemplares similares
-
Comparative mutational evaluation of multiple lung cancers by multiplex oncogene mutation analysis
por: Takahashi, Yuta, et al.
Publicado: (2018) -
Therapeutic strategies for afatinib‐resistant lung cancer harboring HER2 alterations
por: Torigoe, Hidejiro, et al.
Publicado: (2018) -
Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR‐TKIs in non‐small cell lung cancer
por: Sato, Hiroki, et al.
Publicado: (2018) -
Acquired resistance mechanisms to afatinib in HER2‐amplified gastric cancer cells
por: Yoshioka, Takahiro, et al.
Publicado: (2019) -
Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma
por: Namba, Kei, et al.
Publicado: (2019)