Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress

Nucleotide repeat expansions (NREs) are prevalent mutations in a multitude of neurodegenerative diseases. Repeat‐associated non‐AUG (RAN) translation of these repeat regions produces mono or dipeptides that contribute to the pathogenesis of these diseases. However, the mechanisms and drivers of RAN...

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Detalles Bibliográficos
Autores principales: Westergard, Thomas, McAvoy, Kevin, Russell, Katelyn, Wen, Xinmei, Pang, Yu, Morris, Brandie, Pasinelli, Piera, Trotti, Davide, Haeusler, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365928/
https://www.ncbi.nlm.nih.gov/pubmed/30617154
http://dx.doi.org/10.15252/emmm.201809423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365928/
https://www.ncbi.nlm.nih.gov/pubmed/30617154
http://dx.doi.org/10.15252/emmm.201809423

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