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Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids

The fibromuscular stroma of the prostate regulates normal epithelial differentiation and contributes to carcinogenesis in vivo. We developed and characterized a human 3D prostate organoid co-culture model that incorporates prostate stroma. Primary prostate stromal cells increased organoid formation...

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Detalles Bibliográficos
Autores principales: Richards, Zachary, McCray, Tara, Marsili, Joseph, Zenner, Morgan L., Manlucu, Jacob T., Garcia, Jason, Kajdacsy-Balla, Andre, Murray, Marcus, Voisine, Cindy, Murphy, Adam B., Abdulkadir, Sarki A., Prins, Gail S., Nonn, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365938/
https://www.ncbi.nlm.nih.gov/pubmed/30735898
http://dx.doi.org/10.1016/j.isci.2019.01.028