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Prostate Stroma Increases the Viability and Maintains the Branching Phenotype of Human Prostate Organoids
The fibromuscular stroma of the prostate regulates normal epithelial differentiation and contributes to carcinogenesis in vivo. We developed and characterized a human 3D prostate organoid co-culture model that incorporates prostate stroma. Primary prostate stromal cells increased organoid formation...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365938/ https://www.ncbi.nlm.nih.gov/pubmed/30735898 http://dx.doi.org/10.1016/j.isci.2019.01.028 |