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Mps1 is associated with the BRAF(V600E) mutation and predicts poor outcome in patients with colorectal cancer
Colorectal cancer (CRC) with the V600E mutation of B-Raf proto-oncogene serine/threonine kinase (BRAF(V600E)) mutation is insensitive to chemotherapy and is indicative of a poor patient prognosis. Although BRAF inhibitors have a marked effect on malignant melanoma harboring the BRAF(V600E) mutation,...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365956/ https://www.ncbi.nlm.nih.gov/pubmed/30854056 http://dx.doi.org/10.3892/ol.2019.9924 |