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Mps1 is associated with the BRAF(V600E) mutation and predicts poor outcome in patients with colorectal cancer

Colorectal cancer (CRC) with the V600E mutation of B-Raf proto-oncogene serine/threonine kinase (BRAF(V600E)) mutation is insensitive to chemotherapy and is indicative of a poor patient prognosis. Although BRAF inhibitors have a marked effect on malignant melanoma harboring the BRAF(V600E) mutation,...

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Detalles Bibliográficos
Autores principales: Zhang, Yanyan, Dong, Jinyao, Shi, Ruyi, Feng, Liguo, Li, Yike, Cheng, Caixia, Zhang, Ling, Song, Bin, Bi, Yanghui, Huang, He, Kong, Pengzhou, Guo, Jiansheng, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365956/
https://www.ncbi.nlm.nih.gov/pubmed/30854056
http://dx.doi.org/10.3892/ol.2019.9924