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A mathematical model as a tool to identify microRNAs with highest impact on transcriptome changes

BACKGROUND: Rapid changes in the expression of many messenger RNA (mRNA) species follow exposure of cells to ionizing radiation. One of the hypothetical mechanisms of this response may include microRNA (miRNA) regulation, since the amounts of miRNAs in cells also vary upon irradiation. To address th...

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Detalles Bibliográficos
Autores principales: Mura, Marzena, Jaksik, Roman, Lalik, Anna, Biernacki, Krzysztof, Kimmel, Marek, Rzeszowska-Wolny, Joanna, Fujarewicz, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366035/
https://www.ncbi.nlm.nih.gov/pubmed/30727966
http://dx.doi.org/10.1186/s12864-019-5464-0