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Sex-specific regulation of cardiac microRNAs targeting mitochondrial proteins in pressure overload

BACKGROUND: Maladaptive remodeling in pressure overload (PO)-induced left ventricular hypertrophy (LVH) may lead to heart failure. Major sex differences have been reported in this process. The steroid hormone 17β-estradiol, along with its receptors ERα and ERβ, is thought to be crucial for sex diffe...

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Detalles Bibliográficos
Autores principales: Sanchez-Ruderisch, Hugo, Queirós, Ana Maria, Fliegner, Daniela, Eschen, Claudia, Kararigas, Georgios, Regitz-Zagrosek, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366038/
https://www.ncbi.nlm.nih.gov/pubmed/30728084
http://dx.doi.org/10.1186/s13293-019-0222-1