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Sex-specific regulation of cardiac microRNAs targeting mitochondrial proteins in pressure overload
BACKGROUND: Maladaptive remodeling in pressure overload (PO)-induced left ventricular hypertrophy (LVH) may lead to heart failure. Major sex differences have been reported in this process. The steroid hormone 17β-estradiol, along with its receptors ERα and ERβ, is thought to be crucial for sex diffe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366038/ https://www.ncbi.nlm.nih.gov/pubmed/30728084 http://dx.doi.org/10.1186/s13293-019-0222-1 |