The YoaW signal peptide directs efficient secretion of different heterologous proteins fused to a StrepII-SUMO tag in Bacillus subtilis

BACKGROUND: Heterologous gene expression is well established for various prokaryotic model systems. However, low yield, incorrect folding and instability still impede the production of soluble, bioactive proteins. To improve protein production with the Gram-positive host Bacillus subtilis, a secreto...

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Detalles Bibliográficos
Autores principales: Heinrich, Janine, Drewniok, Chris, Neugebauer, Eva, Kellner, Harald, Wiegert, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366066/
https://www.ncbi.nlm.nih.gov/pubmed/30732606
http://dx.doi.org/10.1186/s12934-019-1078-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366066/
https://www.ncbi.nlm.nih.gov/pubmed/30732606
http://dx.doi.org/10.1186/s12934-019-1078-0

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