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Rheumatoid arthritis reprograms circadian output pathways

OBJECTIVE: We applied systems biology approaches to investigate circadian rhythmicity in rheumatoid arthritis (RA). METHODS: We recruited adults (age 16–80 years old) with a clinical diagnosis of RA (active disease [DAS28 > 3.2]). Sleep profiles were determined before inpatient measurements of sa...

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Detalles Bibliográficos
Autores principales: Poolman, Toryn M., Gibbs, Julie, Walker, Amy L., Dickson, Suzanna, Farrell, Laura, Hensman, James, Kendall, Alexandra C., Maidstone, Robert, Warwood, Stacey, Loudon, Andrew, Rattray, Magnus, Bruce, Ian N., Nicolaou, Anna, Ray, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366099/
https://www.ncbi.nlm.nih.gov/pubmed/30728072
http://dx.doi.org/10.1186/s13075-019-1825-y