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Rheumatoid arthritis reprograms circadian output pathways
OBJECTIVE: We applied systems biology approaches to investigate circadian rhythmicity in rheumatoid arthritis (RA). METHODS: We recruited adults (age 16–80 years old) with a clinical diagnosis of RA (active disease [DAS28 > 3.2]). Sleep profiles were determined before inpatient measurements of sa...
Autores principales: | Poolman, Toryn M., Gibbs, Julie, Walker, Amy L., Dickson, Suzanna, Farrell, Laura, Hensman, James, Kendall, Alexandra C., Maidstone, Robert, Warwood, Stacey, Loudon, Andrew, Rattray, Magnus, Bruce, Ian N., Nicolaou, Anna, Ray, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366099/ https://www.ncbi.nlm.nih.gov/pubmed/30728072 http://dx.doi.org/10.1186/s13075-019-1825-y |
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