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HDAC4 gene silencing alleviates epilepsy by inhibition of GABA in a rat model

OBJECTIVES: Despite the availability of effective antiepileptic drugs, epileptic patients still suffer from intractable seizures and adverse events. Better control of both seizures and fewer side effects is needed in order to enhance the patient’s quality of life. We performed the present study with...

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Detalles Bibliográficos
Autores principales: Zhang, Yinian, Dong, Hua-Teng, Duan, Lei, Niu, Liang, Yuan, Guo-Qiang, Dai, Jun-Qiang, Hou, Bo-Ru, Pan, Ya-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366349/
https://www.ncbi.nlm.nih.gov/pubmed/30787615
http://dx.doi.org/10.2147/NDT.S181669