Neuroprotective potential of ketamine prevents developing brain structure impairment and alteration of neurocognitive function induced via isoflurane through the PI3K/AKT/GSK-3β pathway

BACKGROUND: The aim of the current experimental study was to scrutinize the neuroprotective effect of ketamine on the isoflurane (iso)-induced cognitive dysfunction in rats via phosphoinositide 3 kinase (PI3K)/protein kinase B (AKT)/glycogen synthase kinase 3β (GSK-3β) pathway. MATERIALS AND METHODS...

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Detalles Bibliográficos
Autores principales: Wang, Ruiwei, Zhang, Zihao, Kumar, Mukesh, Xu, Guangming, Zhang, Mengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366353/
https://www.ncbi.nlm.nih.gov/pubmed/30787593
http://dx.doi.org/10.2147/DDDT.S188636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366353/
https://www.ncbi.nlm.nih.gov/pubmed/30787593
http://dx.doi.org/10.2147/DDDT.S188636

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