LiBiNorm: an htseq-count analogue with improved normalisation of Smart-seq2 data and library preparation diagnostics

Protocols for preparing RNA sequencing (RNA-seq) libraries, most prominently “Smart-seq” variations, introduce global biases that can have a significant impact on the quantification of gene expression levels. This global bias can lead to drastic over- or under-representation of RNA in non-linear len...

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Detalles Bibliográficos
Autores principales: Dyer, Nigel P., Shahrezaei, Vahid, Hebenstreit, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366399/
https://www.ncbi.nlm.nih.gov/pubmed/30740268
http://dx.doi.org/10.7717/peerj.6222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366399/
https://www.ncbi.nlm.nih.gov/pubmed/30740268
http://dx.doi.org/10.7717/peerj.6222

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