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Development of a novel, high-affinity ssDNA trypsin inhibitor

Inhibitors of serine proteases are not only extremely useful in the basic research but are also applied extensively in clinical settings. Using Systematic Evolution of Ligands by Exponential Enrichment (SELEX) approach we developed a family of novel, single-stranded DNA aptamers capable of specific...

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Detalles Bibliográficos
Autores principales: Malicki, Stanislaw, Ksiazek, Miroslaw, Majewski, Pawel, Pecak, Aleksandra, Mydel, Piotr, Grudnik, Przemyslaw, Dubin, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366424/
https://www.ncbi.nlm.nih.gov/pubmed/30727784
http://dx.doi.org/10.1080/14756366.2019.1569648