Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways

Alternative lengthening of telomeres (ALT) is a telomerase-independent but recombination-dependent pathway that maintains telomeres. Here, we describe an assay to visualize ALT-mediated telomeric DNA synthesis in ALT-associated PML bodies (APBs) without DNA-damaging agents or replication inhibitors....

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Min, Yadav, Tribhuwan, Ouyang, Jian, Lan, Li, Zou, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366628/
https://www.ncbi.nlm.nih.gov/pubmed/30673617
http://dx.doi.org/10.1016/j.celrep.2018.12.102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366628/
https://www.ncbi.nlm.nih.gov/pubmed/30673617
http://dx.doi.org/10.1016/j.celrep.2018.12.102

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