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TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis

Ten-eleven translocation (Tet) enzymes (Tet1/2/3) mediate 5-methylcytosine (5mC) hydroxylation, which can facilitate DNA demethylation and thereby impact gene expression. Studied mostly for how mutant isoforms impact cancer, the normal roles for Tet enzymes during organogenesis are largely unknown....

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Detalles Bibliográficos
Autores principales: Lan, Yahui, Pan, Heng, Li, Cheng, Banks, Kelly M., Sam, Jessica, Ding, Bo, Elemento, Olivier, Goll, Mary G., Evans, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366638/
https://www.ncbi.nlm.nih.gov/pubmed/30650362
http://dx.doi.org/10.1016/j.celrep.2018.12.076