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TETs Regulate Proepicardial Cell Migration through Extracellular Matrix Organization during Zebrafish Cardiogenesis
Ten-eleven translocation (Tet) enzymes (Tet1/2/3) mediate 5-methylcytosine (5mC) hydroxylation, which can facilitate DNA demethylation and thereby impact gene expression. Studied mostly for how mutant isoforms impact cancer, the normal roles for Tet enzymes during organogenesis are largely unknown....
Autores principales: | Lan, Yahui, Pan, Heng, Li, Cheng, Banks, Kelly M., Sam, Jessica, Ding, Bo, Elemento, Olivier, Goll, Mary G., Evans, Todd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366638/ https://www.ncbi.nlm.nih.gov/pubmed/30650362 http://dx.doi.org/10.1016/j.celrep.2018.12.076 |
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