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Sepsis induces long-lasting impairments in CD4(+) T-cell responses despite rapid numerical recovery of T-lymphocyte populations

Massive apoptosis of lymphocytes is a hallmark of sepsis. The resulting immunosuppression is associated with secondary infections, which are often lethal. Moreover, sepsis-survivors are burdened with increased morbidity and mortality for several years after the sepsis episode. The duration and clini...

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Detalles Bibliográficos
Autores principales: Ammer-Herrmenau, Christoph, Kulkarni, Upasana, Andreas, Nico, Ungelenk, Martin, Ravens, Sarina, Hübner, Christian, Kather, Angela, Kurth, Ingo, Bauer, Michael, Kamradt, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366777/
https://www.ncbi.nlm.nih.gov/pubmed/30730978
http://dx.doi.org/10.1371/journal.pone.0211716