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Sepsis induces long-lasting impairments in CD4(+) T-cell responses despite rapid numerical recovery of T-lymphocyte populations
Massive apoptosis of lymphocytes is a hallmark of sepsis. The resulting immunosuppression is associated with secondary infections, which are often lethal. Moreover, sepsis-survivors are burdened with increased morbidity and mortality for several years after the sepsis episode. The duration and clini...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366777/ https://www.ncbi.nlm.nih.gov/pubmed/30730978 http://dx.doi.org/10.1371/journal.pone.0211716 |